INCORPORATION OF CURCUMIN INTO NANOSTRUCTURED SYSTEMS: A REVIEW
Keywords:Curcumin. Nanotechnology. Physicochemical characterization.
Curcumin is a polyphenolic compound extracted from the rhizome of Curcuma longa Linn with diverse pharmacological properties, such as anti-inflammatory, antioxidant, anticancer, antimicrobial, hepatoprotective, hypoglycemic, among others, being interesting to the development of products containing curcumin, which will bring health benefits. Curcumin can be used as a natural additive to replace the synthetic, as colorants, antioxidants and antimicrobials, and also due to its pharmacological properties. However, their incorporation into functional foods or food supplement is hampered by its low water solubility, susceptibility to alkaline conditions, light, heat and oxidation. Nanotechnology is an emerging field to improve the poor solubility, stability and bioavailability of curcumin. Several types of nanoparticles have been found to be suitable for the encapsulation of curcumin. This article reviews the nanostructured systems containing curcumin, like polymeric nanoparticles, solid lipid nanoparticles, liposome and nanoemulsions. Besides the nanoencapsulation techniques and physicochemical characteristics of these carriers.
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