MICROENCAPSULATION OF PROBIOTIC CULTURES: PRINCIPLES OF SPRAY DRYING METHOD
DOI:
https://doi.org/10.5902/2179460X19742Keywords:
Probiotic. Microencapsulation. Spray drying.Abstract
Probiotic microorganisms are known to provide a number of benefits to consumer health, primarily through the maintenance of balance and composition of the gastrointestinal tract. However, for the health benefits to be achieved, should remain viable probiotics in sufficient quantity in the food until the time of consumption, in addition to being able to survive passage through the gastrointestinal tract. Due to these factors microencapsulation methods have been applied in order to protect probiotics against adverse conditions they are exposed, improving their survival. The technique of spray drying is one commonly used for encapsulation of food ingredients, it offers some advantages, such as relatively low cost, ease of operation, high production rates and possibility of application in industrial scale. In this context, the aim of this work is to provide an overview of the importance and benefits of microencapsulation of probiotic cultures emphasizing the principles of métodode spray drying.
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References
AXELSSON, L. Lactic acid bacteria: classification and physiology. In: SALMINEN, S. et al. Lactic acid bacteria: microbiological and functional aspects. 3.ed. New York: Marcel Dekker, 2004. p.1-66.
ANANTA, E.; VOLKERT, M.; KNORR, D. Cellular injuries and storage stability of spray-dried Lactobacillus rhamnosus GG. International Dairy Journal, v. 15, p. 399- 409, 2005.
ANAL, A. K.; SINGH, H. Recent advances in microencapsulation of probiotics for industrial applications and targeted delivery. Food Science and Technology, v. 18, p. 240-251, 2007.
AZEREDO, H. M. C. Encapsulação: aplicação à tecnologia de alimentos. Alimentos e Nutrição, v. 16, n. 1, p. 89-95, 2005.
BANSODE, S. S.; BANARJEE, S. K.; GAIKWAD, D. D.; JADHAV, S. L.; THORAT, R. M. Microencapsulation: a review. International Journal of Pharmaceutical Sciences Review and Research, v. 1, n. 2, p. 38-43, 2010.
BOYLSTON, T. D.; VINDEROLA, C. G.; GHODDUSI, H. B.; REINHEIMER, J. A. Incorporation of bifidobacteria into cheeses: challenges and rewards. International Dairy Journal, v. 14, p. 375-387, 2004. BRASIL. Agência Nacional de Vigilância Sanitária. Alimentos com alegações de propriedades funcionais e ou de saúde. Disponívelem:http://s.anvisa.gov.br/wps/s/r/wuE. Acesso em: 18 de outubro de 2013.
BURGAIN, J.; GAIANI, C.; LINDER, M.; SCHER, J. Encapsulation of probiotic living cells: from laboratory scale to industrial applications. Journal of Food Engineering, v. 104, p. 467-483, 2011.
CASTRO-CISLAGHI, F. P.; SILVA, C. R. E.; FRITZEN-FREIRE, C. B.; LORENZ, J. G.; SANT’ANNA, E. S. Bifidobacterium Bb-12 microencapsulated by spray drying with whey: survival under simulated gastrointestinal conditions, tolerance to NaCl, and viability during storage. Journal of Food Engineering, v. 113, p. 186–193, 2012.
COOK, M. T.; TZORTZIS, G.; CHARALAMPOPOULOS, D.; KHUTORYANSKIY, V. V. Microencapsulation of probiotics for gastrointestinal delivery. Journal of Controlled Release, v. 162, p. 56-67, 2012.
CORCORAN, B. M.; ROSS, R. P.; FITZGERALDS, G. F.; STANTON, C. Comparative survival of probiotic lactobacilli spray-dried in the presence of prebiotic substances. Journal of Applied Microbiology, v. 96, p. 1024-1039, 2004. CORREIA, M. I. T. D.; LIBOREDO, J. C.; CONSOLI, M. L. D. The role of probióticos in gastrointestinal surgery. Nutrition, v. 28, p. 230–234, 2012. CHANPAGNE, C.; FUSTIER, P. Microencapsulation for the improved delivery of bioactive compounds into foods. Current Opinion in Biotechnology, v. 18, p. 184-190, 2007.
CHÁVARRI, M.; MARAÑÓN, I.; ARES, R.; IBÁÑEZ, F. C.; MARZO, F.; VILLARÁN, M. D. C. Microencapsulation of a probiotic and prebiotic in alginate-chitosan capsules improves survival in simulated gastro-intestinal conditions. International Journal of Food Microbiology, v. 142, p. 185-189, 2010.
CRITTENDEN, R. et al. Adhesion of Bifidobacteria to granular starch and its implications in probiotic technologies. Applied and Environmental Microbiology, v.67, p.3469-3475, 2001.
DIANAWATI, D.; MISHRA, V.; SHAH, N. P. Survival of Bifidobacterium longum1941 microencapsulated with proteins and sugars after freezing and freeze drying. Food Research International, v. 51, p. 503-509, 2013.
DOHERTY, S B.; GEE, V. L.; ROSS, R. P.; STANTON, C.; FITZGERALD, G. F.; BRODKORB, A. Development and characterization of whey protein micro-beads as potential matrices for probiotic protection. Food Hydrocolloids, v. 25, p. 1604-1617, 2011.
DESAI, K. G.H.; PARKA, H. J.Recent developments in microencapsulation of food ingredients. Drying Technology, v. 23, n. 7, p. 1361-1394, 2005.
DESMOND, C.; ROSS, R. P.; O’CALLAGHAN, E.; FITZGERALD, G., STANTON, C. Improved survival of Lactobacillus paracasei NFBC 338 in spray-dried powders containing gum acacia. Journal of Applied Microbiology, v. 93, p. 1003-1011, 2002.
DEPYDERE, F.; DEWETTINCK, K.; RONSSE, F.; PIETERS, J. Food powder microencapsulation: principles, problems and opportunities. Applied Biotechnology Food Science and Policy, v.1, n.2, p.75-94, 2003.
De VOS, P.; FAAS, M. M.; SPASOJEVIC, M.; SIKKEMA, J. Encapsulation for preservation of functionality and targeted delivery of bioactive food components. International Dairy Journal, v. 20, p. 292-302, 2010.
DING, W. K.; SHAH, N. P. Effect of various encapsulating materials on the stability of probiotic bacteria. Journal of Food Science, v. 74, p. M100-M107, 2009.
ESTEVINHO, B.; ROCHA, F.; SANTOS, L.; ALVES, A. Microencapsulation with chitosan by spray drying for industry applications - a review. Trends in Food Science & Technology, v. 31, p. 138-155, 2013.
FANG, Z.; BHANDARI, B. Encapsulation of polyphenols: a review. Trends in Food Science & Technology, v. 21, n. 10, p, 510-523, 2010.
FAO/WHO. Probióticos en los alimentos. Propiedades saludables y nutricionales y directrices para la evaluación: Estudio FAO Alimentación y Nutrición, Roma, 2006. 45p. Disponível em: ftp://ftp.fao.org/docrep/fao/009/a0512s/a0512s00.pdf. Acesso em 11 de outubro de 2014. FÁVARO-TRINDADE, C. S.; PINHO, S. C.; ROCHA, G. A. Revisão: Microencapsulação de ingredientes alimentícios. Brazilian Journal of Food Technology, v. 11, p. 103-112, 2008.
FRITZEN-FREIRE, C. B; PRUDÊNCIO, E. S.; AMBONI, R. D. M. C; PINTO, S. S; NEGRÃO-MURAKAMI, A.; MURAKAMI, F. S. Microencapsulation of bifidobacteria by spray drying in the presence of prebiotics. Food Research International, v. 45, p. 306-312, 2012.
GBASSI, G. K.; VANDAMME, T.; ENNAHAR, S.; MARCHIONI, E. Microencapsulation of Lactobacillus plantarum spp in an alginate matrix coated withwhey proteins. International Journal of Food Microbiology, v. 129, p. 103-105, 2009. GHANDI, A.; POWELL, I. B.; HOWES, T.; CHEN, X. D.; ADHIKARI, B. Effect of shear rate and oxygen stresses on the survival of Lactococcus lactis during the atomization and drying stages of spray drying: a laboratory and pilot scale study. Journal of Food Engineering, v. 113, p. 194-200, 2012.
GOLOWCZYCA, A. M.; SILVA, J.; TEIXEIRA, P.; De ANTONI, G. L.; ABRAHAM, A.G. Cellular injuries of spray-dried Lactobacillus spp. isolated from kefir and their impact on probiotic properties. International Journal of Food Microbiology, v. 144, p. 556-560, 2011.
GHARSALLAOUI, A.; ROUDAUT, G.; CHAMBIN, O.; VOILLEY, A.; SAUREL, R. Applications of spray-drying in microencapsulation of food ingredients: an overview. Food Research International, v. 40, p. 1107-1121, 2007.
KISSEL, T.; MARETSCHEK, S.; PACKHAUSER, C.; SCHNIEDERS, J.; SEIDEL, N. Microencapsulation techniques for parenteral depot systems and their application in the pharmaceutical industry. In: BENITA, S. Microencapsulation: Methods and Industrial Applications. 2º edição. Boca Raton, CRC Press Taylor E Francis Group, pp. 104, 2006.
KIM, S.; SEUNG, Y. C.; KIM, S. H.; SONG, O.; SHIND, S.; CHA, D. S.; PARK, H. J.Effect of microencapsulation on viability and other characteristics in Lactobacillus acidophilus ATCC 43121. LWT - Food Science and Technology, v. 41, p. 493-500, 2008. KING, A.H. Encapsulation of Food ingredients: a review of available technology, focusing on hydrocolloids. In: RISCH, S.J.; REINECCIUS, G.A. (Eds.). Encapsulation and controlled release of food ingredients. Washington DC, American Chemical Society, pp.213-220, 1995.
KOMATSU, T. R.; BURITI, F. C. A.; SAAD, S. M. I. Inovação, persistência e criatividade superando barreiras no desenvolvimento de alimentos probióticos. Revista Brasileira de Ciências Farmacêuticas, v. 44, p. 329-347, 2008.
KUANG, S. S.: OLIVEIRA, J. C.; CREAN, A. M. Microencapsulation as a tool for incorporating bioactive ingredients into food. Critical Reviews in Food Science and Nutrition, v. 50, n. 10, p. 1913-1918, 2010.
MADENE, A.; MURIEL, J.; SCHER, J.; DESOBRY, S. Flavour encapsulation and controlled release – a review. International Journal of Food Science and Technology, v. 41, n. 1, p. 1-21, 2006.
MAKINEN, K.; BERGER, B.; BEL-RHLID, R; ANANTA, E. Science and technology for the mastership of probiotic applications in food product. Journal of Biotechnology, v. 162, p. 356-365, 2012.
MORTAZAVIAN, A.; RAZAVI, S. H.; EHSANI, M. R.; SOHRABVANDI, S. Principles and methods of microencapsulation of prebiotic microorganisms. Iranian Journal of Biotechnology, v. 5, p. 1-18, 2007.
NAG, A.; HAN, K.; SING, H. Microencapsulation of probiotic bacteria using pH-induced gelation of sodium caseinate and gellan gum. International Dairy Journal, v. 21, p. 247-253, 2011.
NAZZARO, F.; PIERANGELO, O.; FRATIANNI, F.; COPPOLA, R. Microencapsulation in food science and biotechnology. Current Opinion in Biotechnology, v. 23, p. 182-186, 2012.
OBEIDAT, W. N. Recent patents review in microencapsulation of pharmaceuticals using de emulsion solvent removal methods. Recent Patents on Drug Delivery & Formulation, v. 3, n. 3, p. 178-192, 2009.
OKURO, P. K.; THOMAZINI, M.; BALIEIRO, J. C. C.; LIBERAL, R. D. C. O.; FÁVARO-TRINDADE, C. S. Co- encapsulation of Lactobacillus acidophilus with inulin or polydextrose in solid lipid microparticles provides protection and improves stability. Food Research International, v. 53, p. 96-103, 2013.
PUUPPONEN-PIMIA, R.; AURA, A. M.; OKSMAN-CALDENTEY, K. M.; MYLLARINEN, P.; SAARELA, M.; MATTILA-SANDHOLM, T.; POUTANEN, K. Development of functional ingredients for gut health. Trends in Food Science and Technology, v. 13, p. 3-11, 2002.
PLESSAS, S.; BOSNEA, L.; ALEXOPOULOS, A.; BEZIRTZOGLOU, E. Potential effects of probiotics in cheese and yogurt production: A review. Engineering in Life Sciences, v. 12, p. 433-440, 2012.
RANADHEERA, R. D. C. S.; BAINES, S. K.; ADAMS, M. C. Importance of food in probiotic efficacy. Food Research International, v. 43, p. 1-7, 2010. RATHORE, S.; DESAI, P. M.; LIEW, C. V.; CHAN, L. W.; HENG, P. W. S. Microencapsulation of microbial cells. Journal of Food Engineering, v. 116, p. 369-381, 2013.
RÉ, M. I. Formulating drug delivery systems by spray drying. Drying Thecnology, v. 24, n. 4, p. 433-446, 2006.
RÉ, M.I. Microencapsulation by spray drying. Drying Technology, v.16, p.1195-1236, 1998.
RIVERA-ESPINOZA, Y.; GALLARDO-NAVARRO, Y. Non-diary probiotic products.
Food Microbiology, v. 27, p. 1-11, 2010.
RODRÍGUEZ-HUEZO, M. E.; DURAN-LUGO, R.; PRADO-BARRAGAN, L. A.; CRUZ-SOSA, F.; LOBATO- CALLEROS, C.; ALVAREZ-RAMÍREZ, J.; VERNON-CARTER, E. J. Pre-selection of protective colloids for enhanced viability of Bifidobacterium bifidum following spray-drying and storage, and evaluation of aguamiel as thermoprotective prebiotic. Food Research International, v. 40, p. 1299-1306, 2007.
SAAD, N.; DELATTRE, C.; URDACI, M.; SCHMITTER, J. M.; BRESSOLLIE, P. An overview of the last advances in probiotic and prebiotic field. LWT - Food Science and Technology, v. 50, p. 1-16, 2013.
SEMYONOV, D.; RAMON, O.; KAPLUN, Z.; LEVIN-BRENER, L.; GUREVICH, N.;
SHIMONI, E. Microencapsulation of Lactobacillus paracasei by spray freeze drying. Food Research International, v. 43, p. 193-202, 2010.
SHAH, N. P. Functional cultures and health benefits. International Dairy Journal, v. 17, p. 1262-1277, 2007.
SILVA, C.; RIBEIRO, A.; FERREIRA, D.; VEIGA, F. Administração oral de proteínas e peptídeos: II. Aplicação de métodos de microencapsulação. Brazilian Journal of Pharmaceutical Sciences, v. 39, n. 1, p. 1-9, 2003.
SUAVE, J.; DALL’AGNOL, E. C.; PEZZIN, A. P. T.; SILVA, D. A. K.; MEIER, M. M, SOLD, V. Microencapsulação: inovação em diferentes áreas. Health and Environment Journal, v. 7, n. 2, p.12-20, 2006.
TIWARI, S.: GOEL, A.; JHA, K. K.; SHARMA, A. Microencapsulation techniques and its application: a review. The Pharma Research, v. 3, n. 12, 2010.
TRINDADE, C. S. F.; PINHO, S. C.; ROCHA, G. A. Review: microencapsulation of food ingredients. Brazilian Journal of Food Technology, v. 11, n. 2, p. 103-109, 2008.
WEICHSELBAUM, E. Probiotics and health: a review of the evidence. Nutrition Bulletin, v. 34, p. 340-373, 2009.
WILSON, N.; SHAH, N. P. Microencapsulation of vitamins. ASEAN Food Journal, v. 14, n. 1, p. 1-14, 2007.
YING, D. Y.; SANGUANSRI, L.; WEERAKKODY, R.; AUGUSTIN, M. A. Enhanced survival of spray-dried microencapsulated Lactobacillus rhamnosus GG in the presence of glucose. Journal of Food Engineering, v. 109, p. 597-602, 2012.
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