EMULSIFICATION/INTERNAL IONIC GELATION: ALTERNATIVE FOR MICROENCAPSULATION BIOACTIVE COMPOUNDS
DOI:
https://doi.org/10.5902/2179460X19739Keywords:
Bioactive. Emulsification. Microencapsulation. Stability.Abstract
The application of bioactive compounds in food have attracted the interest of the industry due to potential health benefits to humans. However, the efficiency depends on the stability, bioactivity and bioavailability of these active ingredients in the food matrix. The unpleasant taste and instability limit the application of these compounds. The use of encapsulated bioactive instead of free compounds can effectively alleviate these problems. The encapsulation technology being used in many different active compounds is the emulsification/internal ionic gelation, which is an important alternative for improving the stability and application in food.
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ALMAJANO, M. P., CARBÓ, R., JIMÉNEZ, J. A. L., GORDON, M. H. Antioxidant and antimicrobial activities of tea infusions, Food Chemistry, v. 108, n. 1, p. 55-63, 2008.
BELYAEVA, E., VALLE, D. D., PONCELET, D. Immobilization of α-chymotrypsin in κ-carrageenan beads prepared with the static mixer, Enzyme and Microbial Technology, v. 34, n. 2, p. 108-113, 2004.
BIESALSKI, H.-K., DRAGSTED, L.O., ELMADFA, I., GROSSKLAUS, R., MÜLLER, M., SCHRENK, D., WALTER, P., WEBER, P. Bioactive compounds: definition and assessment of activity, Nutrition, v. 25, n. 11–12, pp. 1202–1205, 2009.
BUSTOS, R., ROMO, L., YÁÑEZ, K., DÍAZ, G., ROMO, C. Oxidative stability of carotenoid pigments and polyunsaturated fatty acids in microparticulate diets containing krill oil for nutrition of marine fish larvae, Journal of Food Engineering, v. 56, n. 2–3, p. 289-293, 2003.
CHAKRABORTY, S., SHUKLA, D., MISHRA, B., SINGH, S. Lipid—an emerging platform for oral delivery of drugs with poor bioavailability, Eur. J. Pharm. Biopharm, v. 73, n. 1-15, 2009.
CHAN, L.W.; LEE, H.Y.; HENG, P.W.S. Production of alginate microspheres by internal gelation using an emulsification method, International Journal of Pharmaceutics, 242 (1–2), 259-262, 2002.
CHAN, L. W.; LEE, H. Y.; HENG, P. W.S. Mechanisms of external and internal gelation and their impact on the functions of alginate as a coat and delivery system, Carbohydrate Polymers, 63 (2), 176-187, 2006.
CHO, Y.H., SHIM, H.K., PARK, J. Encapsulation of fish oil by an enzymatic gelation process using transglutaminase cross-linked proteins, Journal of Food Science, v. 68, p. 2717–2723, 2006.
COSTA, B. S. Micropartículas produzidas por gelificação iônica recobertas com gelatina de peixe e isolado proteico de soja. Dissertação (Mestrado em alimentos e nutrição) - Universidade Estadual de Campinas, Campinas-SP, 2014.
CROWE, F.L., RODDAM, A.W., KEY, T.J., APPLEBY, P.N., OVERVAD, K., JAKOBSEN, M.U., et al. Fruit and vegetable intake and mortality from ischaemic heart disease: Results from the European prospective investigation into cancer and nutrition (EPIC)-heart study, European Heart Journal, v. 32, pp. 1235–1243, 2011.
CRUZ, Z., GARCÍA-ESTRADA, C., OLABARRIETA, I., RAINIERI, S. Chapter 16 - Lipid Nanoparticles: Delivery System for Bioactive Food Compounds, In Microencapsulation and Microspheres for Food Applications, edited by Leonard M.C. Sagis, Academic Press, San Diego, p. 313-331, 2015.
EL-ABBASSI, A., NEVES, M.A., KOBAYASHI, I., HAFIDI, A., NAKAJIMA, M. Preparation and characterization of highly stable monodisperse argan oil-in-water emulsions using microchannel emulsification, Eur J Lipid Sci Technol, v. 115, pp. 224–231, 2013.
ESPÍN, J.C., GARCÍA-CONESA, M.T., TOMÁS-BARBERÁN, F.A. Nutraceuticals: facts and fiction, Phytochemistry, 68, 2986-3008, 2007.
GRAAF, S. V. D., SCHROËN, C.G.P.H, BOOM, R.M. Preparation of double emulsions by membrane emulsification—a review, Journal of Membrane Science, v. 251, n. 1–2, pp. 7-15, 2005.
KAUR CH., KAPOOR, H.C. Antioxidants in fruits and vegetables—the millennium's health, International Journal of Food Science and Technology, 36, pp. 703–725, 2001.
KAUSHIK, P., DOWLING, K., BARROW, C. J., ADHIKARI, B. Microencapsulation of omega-3 fatty acids: A review of microencapsulation and characterization methods, Journal of Functional Foods, Available online 4 July 2014.
KHALID, N., KOBAYASHI, I., NEVES, M. A., UEMURA, K., NAKAJIMA, M., NABETANI, H. Monodisperse W/O/W emulsions encapsulating l-ascorbic acid: Insights on their formulation using microchannel emulsification and stability studies, Colloids and Surfaces A: Physicochemical and Engineering Aspects, v. 458, pp. 69-77, 2014.
KLINKESORN, U., SOPHANODORA, P., CHINACHOTI, P., DECKER, E. A., MCCLEMENTS, D. J. Encapsulation of emulsified tuna oil in two-layered interfacial membranes prepared using electrostatic layer-by-layer deposition, Food Hydrocolloids, v. 19, n. 6, p. 1044-1053, 2005.
KRIS-ETHERTON, P.M., HECKER, K.D., BONANOME, A., COVAL, S.M., BINKOSKI, A.E., HILPERT, K.F., GRIEL, A.E., ETHERTON, T.D. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer, Am. J. Med., v. 113, n. 9, pp. 71–88, 2002.
LAINE, P., TOPPINEN, E., KIVELÄ, R., TAAVITSAINEN, V., KNUUTILA, O., SONTAG-STROHM, T., JOUPPILA, KIRSI., LOPONEN, J. Emulsion preparation with modified oat bran: Optimization of the emulsification process for microencapsulation purposes, Journal of Food Engineering, v. 104, n. 4, p. 538-547, 2011.
LAM, P.L., GAMBARI, R. Advanced progress of microencapsulation technologies: In vivo and in vitro models for studying oral and transdermal drug deliveries, Journal of Controlled Release, v. 178, p. 25-45, 2014.
LUPO, B. et al. Preparation of alginate microspheres by emulsification/internal gelation to encapsulate cocoa polyphenols, Food Hydrocolloids, 38, 56-65, 2014.
McCLEMENTS, D.J. Emulsion design to improve the delivery of functional lipophilic components, Ann. Rev. Food Sci. Technol, v. 1, n. 241-269, 2010.
McCLEMENTS, D.J. Selection of Delivery Systems: Case Studies In Nanoparticle- and Microparticle-based Delivery Systems, Edited by: CRC Press, pp. 401–452, 2014.
MUKAI-CORRÊA, R.; PRATA, A.S.; ALVIM, I.D., GROSSO, C.R.F. Controlled release of protein from hydrocolloid gel microbeads before and after drying, Current Drug Delivery, v. 1, n. 3, p. 265-273, 2004.
MUNIN, A., EDWARDS-LÉVY, F. Encapsulation of natural polyphenolic compounds: a review, Pharmaceutics, v. 3, p. 793–829, 2011.
NEVES, M. A., HASHEMI, J., PRENTICE, C. Development of novel bioactives delivery systems by micro/nanotechnology, Current Opinion in Food Science, v. 1, p. 7-12, 2015.
O'DONNELL, P. B.; MCGINITY, J. W. Preparation of microspheres by the solvent evaporation technique, Advanced Drug Delivery Reviews, 28 (1), 25-42, 1997.
OKURO, P. K., FURTADO, G. F., SATO, A. C. K., CUNHA, R. L. Structures Design For Protection And Vehiculation Of Bioactives, Current Opinion in Food Science, Available online 18 September 2015.
PONCELET, et al. Production of alginate beads by emulsification/ internal getation. I.Methodology. Applied Microbiology and Biotechnology, v. 38, n.1, p. 39-45, 1992.
PONCELET, D. Production of alginate beads by emulsification/internal gelation. Bioartificial Organs Iii: Tissue Sourcing, Immunoisolation, and Clinical Trials, 944, pp. 74–82, 2001.
PONCELET, D., BABAK, V., DULIEU, C., PICOT, A. A physico-chemical approach to production of alginate beads by emulsification-internal ionotropic gelation, Colloids and Surfaces A: Physicochemical and Engineering Aspects, v. 155, n. 2–3, p. 171-176, 1999.
RABE, S., KRINGS, U., BERGER, R. G. Influence of oil-in-water emulsion characteristics on initial dynamic flavour release, J Sci Food Agric, v. 83, pp. 1124–1133, 2003.
RÉ, M. I., SANTANA, M. H. A., ÁVILA, M. A. Encapsulation Technologies for Modifying Food Performance. In Taylor and Francis Group, LLC, p. 223-275, 2010.
ROCHA-SELMI, G. A., BOZZA, F. T., THOMAZINI, M., BOLINI, H. M.A., FÁVARO-TRINDADE, C. S. Microencapsulation of aspartame by double emulsion followed by complex coacervation to provide protection and prolong sweetness, Food Chemistry, v. 139, n. 1–4, pp. 72-78, 2013.
ROCK, C.L. Carotenoids: biology and treatment, Pharmacology and Therapeutics, v. 75, n. 3, pp. 185–197, 1997.
RODRIGUES-AMAYA, D. A Guide to Carotenoid Analysis in Foods, OMNI Research: ILSI Press: Washington D. C. 1999.
SARKAR, S., GUPTA, S., VARIYAR, P. S., SHARMA, A., SINGHAL, R. S. Irradiation depolymerized guar gum as partial replacement of gum Arabic for microencapsulation of mint oil, Carbohydrate Polymers, v. 90, n. 4, p. 1685-1694, 2012.
SHARIPOVA, A.A., AIDAROVA, S.B., GRIGORIEV, D., MUTALIEVA, B., MADIBEKOVA, G., TLEUOVA, A., MILLER, R. Polymer–surfactant complexes for microencapsulation of vitamin E and its release, Colloids and Surfaces B: Biointerfaces, Available online 10 April 2015.
SHI, J., XUE, S. J., WANG, B., WANG, W., YE, X., QUEK, S. Y. Optimization of formulation and influence of environmental stresses on stability of lycopene-microemulsion, LWT - Food Science and Technology, v. 60, n. 2, p. 999-1008, Part 1, 2015.
TEIXEIRA, V. F. T. et al. Ion exchange kinetics of magnetic alginate ferrogel beads produced by external gelation, Carbohydrate Polymers, 111, 198-205, 2014.
UENOJO, M; MAROSTICA JUNIOR, M. R; PASTORE, G. M. Carotenóides: propriedades, aplicações e biotransformação para formação de compostos de aroma. Quím. Nova [online]. 2007, vol.30, n.3, pp. 616-622.
VOS, P., FAAS, M. M., SPASOJEVIC, M., SIKKEMA, J. Encapsulation for preservation of functionality and targeted delivery of bioactive food components, International Dairy Journal, v. 20, n. 4, p. 292-302, 2010.
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