White and Brown Crystal Sugar dietary: a high consumption effect in D. Melanogater

Authors

DOI:

https://doi.org/10.5902/2179460X74331

Keywords:

Sugar intake, Oxidative stress, Male and female flies, Enzyme activity, Sucrose, Iron

Abstract

The high consumption of sugars in their different forms has been of concern to the International Health organization (WHO). In this study, D. melanogater (born in the dietary medium - Generation F1) male and females were submitted to a white (WS) and brown (BS) Cristal Sugars rich diet. Results obtained indicate an increase in oxidative stress with an increase in the consumption of sugar in the diet, as observed in the increase in the enzymatic activity of SOD, CAT and GPx. These results are corroborated by analyzes of lipid peroxidation (TBARS), carbonyl content and ROS (DCFH), which clearly demonstrate an increase in the formation of reactive oxygen species with the increase in the consumption of sugars both white and brown crystal sugars. Another effect observed by the increase in sugar consumption was the augmentation in glucose levels (white and brown sugars) and in iron levels (brown sugar). In this sense, the high consumption of iron in brown sugar has contributed more strongly to the formation of ROS in D. melanogaster, mainly in females.

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Author Biographies

Aline Castro Caurio, Universidade Federal do Pampa

He has a degree in Pharmacy from the Federal University of Santa María (2013), a master's degree in BIOCHEMISTRY from the Federal University of Pampa (2017). He is currently studying for a Doctorate in Biochemistry at the Federal University of Pampa, at the Laboratorio de Estudios Físico-Químicos y Productos Naturales (LEFQPN), with a period of co-tutelship at the Federal University of Rio Grande do Sul.

Murilo Ricardo Sigal Carriço, Universidade Federal do Pampa

He has a degree in Natural Sciences from the Federal University of Pampa (2018), a master's degree in Biochemistry from the Federal University of Pampa (2021) and a PhD in progress at the same university. She has experience in Biochemistry, with an emphasis on environmental biochemistry, and in Chemistry, with an emphasis on analytical chemistry. 

Jefferson Enderle, Universidade Federal do Pampa

Jefferson Enderle, Universidade Federal do Pampa, Uruguaiana Campus, Uruguaiana, RS

Pharmacy student at the Federal University of Pampa (UNIPAMPA), PDA scholarship holder at the Laboratory of Physical-Chemical Studies and Natural Products (LEFQPN), working on the green synthesis of silver nanoparticles using plant extracts.

Jefferson de Jesus Soares, Universidade Federal do Pampa

 

Laboratory Technician/Area: Chemistry, Federal University of Pampa - UNIPAMPA

Vanusa Manfredini, Universidade Federal do Pampa

She has a PQ2 Productivity Scholarship. She has a degree in Pharmacy with an emphasis on Clinical Analysis from the Federal University of Rio Grande do Sul (2002), a master's degree (2004) and a PhD in Cellular and Molecular Biology from the Federal University of Rio Grande do Sul (2008). She holds a post-doctorate in Pharmaceutical Sciences (2009) from the Graduate Program in Pharmaceutical Sciences (UFRGS). She is currently Associate Professor 3 at the Federal University of Pampa (UNIPAMPA), Uruguaiana Campus. 

Rafael Roehrs, Universidade Federal do Pampa

He has a degree in Industrial Chemistry from the University of Santa Cruz do Sul (2000), a master's degree in Cellular and Molecular Biology from the Federal University of Rio Grande do Sul (2004) and a doctorate in Analytical Chemistry from the Federal University of Santa Maria (2009). He is currently a lecturer on the Natural Sciences - Degree course, the Biochemistry Postgraduate Program and the Science Education Postgraduate Program: Chemistry of Life and Health at the Federal University of Pampa. I am the leader of the Interdisciplinary Research Group in Teaching Practice (GIPPE) and the Laboratory of Environmental and Toxicological Chemical Analysis (LAQAT), and a researcher at the Laboratory of Physical-Chemical Studies and Natural Products (LEFQPN).

Elton Luís Gasparotto Denardin, Universidade Federal do Pampa

He holds a Bachelor's degree in Chemistry from the Federal University of Paraná (1996), a Master's degree in Chemistry from the Federal University of Rio Grande do Sul (2000) and a PhD in Chemistry from the Federal University of Rio Grande do Sul (2004). He is currently Associate Professor IV (DE) at the Federal University of Pampa (UNIPAMPA)/Campus Uruguaiana and a permanent lecturer in the Postgraduate Program in Biochemistry (2011) and the Postgraduate Program in Pharmaceutical Sciences (2021). He has experience in Chemistry, with an emphasis on Physical Chemistry, Natural Products and Nanomaterials, working mainly on the following subjects: natural and synthetic polymers, spectroscopic, chromatographic and thermal analysis techniques, natural products, nanomaterials and neurodegenerative diseases.

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Published

2024-11-22

How to Cite

Caurio, A. C., Carriço, M. R. S., Enderle, J., Soares, J. de J., Manfredini, V., Roehrs, R., & Denardin, E. L. G. (2024). White and Brown Crystal Sugar dietary: a high consumption effect in D. Melanogater. Ciência E Natura, 46, e74331. https://doi.org/10.5902/2179460X74331

Issue

Vol. 46 (2024): Publicação contínua

Section

Chemistry

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