Reviewing the effect of metal complexation upon the antioxidant/antiradical properties of L-ascorbic acid
DOI:
https://doi.org/10.5902/2179460X74574Keywords:
L-ascorbic acid, redox potential, Metal ligandAbstract
L-ascorbic acid is a molecule used in the hydroxylation of various biochemical reactions in cells. Its main function is the hydroxylation of collagen, the fibrillar protein that gives resistance to bones, teeth, tendons and walls of blood vessels. Furthermore, it is a powerful antioxidant, being used to transform reactive oxygen species into inert forms. It is also used in the synthesis of some molecules that serve as hormones or neurotransmitters. In this review, a series of reactions are presented and discussed with the aim to discuss as some chemical parameters such as pH, redox potential, presence of different metal ions and ascorbic acid works effectively as a ligand. Several mechanisms are revisited and aspects as the effect of transition metals over the redox chemistry of acid is presented.
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In particular,
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Editors: Editors should evaluate manuscripts exclusively on the basis of their academic merit. An Editor must not use unpublished information in the editor's own research without the express written consent of the Author. Editors should take reasonable responsive measures when ethical complaints have been presented concerning a submitted manuscript or published paper.
Reviewers: Any manuscripts received for review must be treated as confidential documents. Privileged information or ideas obtained through peer review must be kept confidential and not used for personal advantage. Reviewers should be conducted objectively, and observations should be formulated clearly with supporting arguments, so that Authors can use them for improving the paper. Any selected Reviewer who feels unqualified to review the research reported in a manuscript or knows that its prompt review will be impossible should notify the Editor and excuse himself from the review process. Reviewers should not consider manuscripts in which they have conflicts of interest resulting from competitive, collaborative, or other relationships or connections with any of the authors, companies, or institutions connected to the papers.
