Formulation of a nanoemulsion of the cross-essential oil of Schinus terebinthifolius, Illicium verum and Syzygium aromaticum to obtain silver nanoparticles with antioxidant and anti-inflammatory potential
DOI:
https://doi.org/10.5902/2179460X88027Keywords:
Anethole, Cross, SynthesisAbstract
This study evaluated the chemical profile, antioxidant, and anti-inflammatory activities of silver nanoparticles (AgNPs) synthesized from the nanoemulsion of cross-processed essential oil (CEO) derived from S. terebinthifolius, I. verum, and S. aromaticum (NOE). Chemical constituents were identified via GC-MS analysis. The nanoemulsions were prepared using the phase inversion method, and AgNP synthesis was achieved through the reduction of AgNO₃ utilizing NOE. Antioxidant activity was assessed by the ABTS radical scavenging assay, while anti-inflammatory activity was evaluated through albumin protein denaturation. The predominant compound identified in the OE was trans-anethole. The highest antioxidant activity, with an IC₅₀ of 3.03mg/L, was observed for AgNPs at pH 10. The most effective anti-inflammatory response had an IC₅₀ of 0.12mg/mL. This research provides novel insights into AgNPs synthesized from NOE, demonstrating their potential to enhance the tested biological activities and highlighting the influence of pH on these formulations.
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