In vitro antioxidant potential, phenolic and flavonoids contents of Scutia buxifolia Reissek twigs
DOI:
https://doi.org/10.5902/223658346527Keywords:
Scutia buxifolia, Coronilha, DPPH, Free radicals.Abstract
This work describes the antioxidant evaluation through the DPPH free radical methodology, the determination of polyphenol dosage by the method of Folin-Ciocalteau and the content of flavonoids in crude extract and fractions of the Scutia buxifolia twigs (coronilha). The content of flavonoids and polyphenols ranged from 102.02 ± 0.71 to 318.82 ± 1.62 milligram of pirogallic acid per gram of dry plant and 83.47 ± 0.93 to 140.71 ± 2.14 milligram of rutin per gram of dry plant, respectively. The IC50 required concentration to inhibit the activity of DPPH at 50% was: crude extract > CH2Cl2 > AcOEt > n-BuOH. In this study it was established a high positive correlation between fractions of phenolic compounds and antioxidant activity of these (0.99). These results indicate that S. buxifolia has chemicals that are able to catch free radicals, promising compounds in the search for antioxidant drugs against diseases from oxidative stress, being the n-BuOH and AcOEt fractions the most effective ones.Downloads
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