Leukocyte, erythrocyte, hemoglobin concentration, hemotocrit and bleding cotting counter by prolonged oral and intraperitonial used of Heterothalamus brunioides in Wistar rats

Authors

  • Ana Maria Chagas Núcleo de Pesquisa de Produtos Naturais Centro de Ciências Naturais e Exatas - CCNE Universidade Federal de Santa Maria - UFSM, Santa Maria, RS.
  • Cloé Mendonça Saldanha Núcleo de Pesquisa de Produtos Naturais Centro de Ciências Naturais e Exatas - CCNE Universidade Federal de Santa Maria - UFSM, Santa Maria, RS.
  • Carlos Mario Cunha Departamento de Análises Clínicas do Hospital Veterinário, Centro de Ciências Rurais - CCR, Universidade Federal de Santa Maria - UFSM, Santa Maria, RS.
  • Heleonora B. Vieira Bolsista Colaboradora e de Iniciação à Pesquisa, Universidade Federal de Santa Maria - UFSM, Santa Maria, RS.
  • Janice Sitya Bolsista Colaboradora e de Iniciação à Pesquisa, Universidade Federal de Santa Maria - UFSM, Santa Maria, RS.
  • Mario Kurtz Filho Bolsista Colaboradora e de Iniciação à Pesquisa, Universidade Federal de Santa Maria - UFSM, Santa Maria, RS.

DOI:

https://doi.org/10.5902/2179460X25466

Abstract

In the present work, authors wished to observe possible blood alterations produced by oral route (98 mg/kg weight) and intraperitonial route (40 mg/kg and 98/kg weight) proIonged administrations of Heterothalamus brunioides, Less in Wistar rats. Results analysis proved that, in the estudied paramethers, was no significant alterations.

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References

AZZOLlN, E.L.C., SIMOES, S.R.M. and CHAGAS, A.M. – Métodos de Avaliação do Tempo de Coagulação Sanguínea em Ratos Wistar. 2ª Jornada de Clínica Médica de Santa Maria, RS, 1986.

BAUMGARTNER, R. and LABER, G. – Haematologische untersuchunger biratten mit experimenteller myhoplasma polyarthritis. Zentralberl Babesial parastenkd infektionshr. Hyg Abt I Reihe A, 232: 105-12, 1975.

BRASIL, O.V. FRANCESCHI, J.P. and WAISBICH, E. – Pharmacology of crystalline crotoxim I. toxicity. Men Inst Butantan Simp Intermac, 33:973-980, 1966.

CHAGAS, A.M. SALDANHA, C. and OLIVEIRA, P.R. - Leucometria, Eritrometria e os Teores Plasmáticos de Sódio, de Potássio e de Cálcio, Após o uso prolongado de Ramaria flavo brunnescens em Ratos. Rev. Centro Ciências Rurais, 10(4), 299-306, 1980.

CRESKOFF, A.J., FRITZ-HUGH, T. JR and FARRIS, E.J. – Hematology of the Rat and Standards in "The Rat in laboratory investigation" (E.J. FARRIS and J.Q. GRIFFITHS, eds) pp. 406-420, lipincott. Philadelphia, Pensylvania, 1949.

FISHER, A. - Laboratório de Análises Clinicas, 6ª ed, Buenos Aires, Editora E1 Ateneo, 1954, 246 p.

FONTANA, F. - Traité sur le Vénin de la Vipere sur les Poisons Americaine sur le Lausier Gerise et sur Quelques autres Paisons Vegetalau x, Vol I and III Firinze, 178l.

HEBOLD, V. G. and BLEUEL, H. - Hamatologische standard werte beider weiblichen und mamlichen ratte (Sprague Dawley). Z. Versuchstierkd, 13: 316-320, 1971.

HOEHNE, F.C. - Plantas e substâncias vegetais tóxicas e medicinais. São Paulo, graphcars, 1939, 352 p.

HULSE, E.V. - Quantitative cell counts of the bone marrow and blood their secular variations in the normal adult rat. Acta Haematol . 31:50-63,1964.

JONES, R.A., JENKINS, L.J. JR., COON, R.A. and SIEGEL, J. – Effect of long-term continuous inhalation of ozone on experimental animals. Toxicol: appe Pharmacol, 17: 189-202, 1970.

KOSMA, C. K., WEISBROTH, S. H., STRATMAN, S. L. and CONEJEROS, M. - Normal Biologic valus for long. Evans rats Lab anim. Care, 19:746-55, 1969.

LACERDA, F. - Are Museu Nac. Rio de Janeiro. Ed. Guanabara, 1978, 202 p.

OHSAKA, A. - Hemorragic Necrotizing and Edema: Forming effects of Snake Venouns. Chapter 14, Washington Mac Graw Hill, 1975, 503 p.

POLLARD, C. B. - Venon Research Ghallenge to Various sciences in Venouns. ed. by E. E. Buchey and N, porges publication 44. Am Assoc. Advancement of Science, Washington, D.C. 1956, 5-8 p.

RINGLER, D. H. and DABICH, L. - Hematologic and clinical, Biochemistray. The Laboratory Rat, 1:105-121, 1979.

ROSENFELD, G. - Symptomalogy, Pathology and Tratament of snake bites in South America. In venouns animals and their venouns. Vol II, New York academic pres. 1971, Biochemistray. The Laboratory Rat, 105-121,1979.

SCHALM, O. W., JAIN, N.C. and CARROLL, E.J. - Veterinary Hematology. 3rd ed Lia and Fihger, Philadelfia, Pensylvania,1975, 278;1.

SCHERMAN, H. - Comparative Profilis of Various Strains of Rats Used in long - term juding Studies. Lab anim. Care, 13:793-807, 1963.

SNEDECOR, G.W. and COCHRAN, V.G. - Two or more Randon samples of measurement data. Analysis of variance in: Statistical Universyte Press, 1956. cap 10, p. 246-247.

SWAROOP, A., GRAB, M. and OHSAKA, A. – Hemorragic Necrotizing and Edema-Forming Effects of Snake Venouns. Chapter 14. Washington Mac Graw Hill, 1975, 503 p.

VONDRUSKA, J.F. and GRECO, R.A. - Certaim hematologic and blood chemical values em charles river C D Albino Rats. Bull, Am Soc. Vet. Clin. Pathol, 2: 3 - 7, 1 973 .

WALKER, A. I. I., STEVENSON, D. E. ROBINSON, J.; THORPE, E. and ROBERTS, M. - The toxicity and pharmacodynamics of dieldrim (Hedd), Toxical., appe. Pharmacol, 15:345-373, 1969.

WORDEN, A., NOEL, P.R.B., MAWDESLEY, T.L.E., PALMER, A.K. and FLETCHER, M.A. - Teading studies on lenacil in the rat and dog. Toxicol., appe. Pharmacol, 27: 215-224, 1974.

Published

1987-12-14

How to Cite

Chagas, A. M., Saldanha, C. M., Cunha, C. M., Vieira, H. B., Sitya, J., & Kurtz Filho, M. (1987). Leukocyte, erythrocyte, hemoglobin concentration, hemotocrit and bleding cotting counter by prolonged oral and intraperitonial used of Heterothalamus brunioides in Wistar rats. Ciência E Natura, 9(9), 67–76. https://doi.org/10.5902/2179460X25466

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