Music therapy, a non-pharmacological intervention that can improve the quality of life in patients with Alzheimer's disease: a systematic review
DOI:
https://doi.org/10.5902/2236583472055Keywords:
Alzheimer disease, Dementia, Music therapy, Music, Systematic reviewAbstract
Objective: This study aims to describe the results obtained from music/music therapy interventions in patients with Alzheimer's disease. Methods: A literature search was conducted in the Virtual Health Library (VHL) and PubMed, using the following terms: "Alzheimer's disease" AND "dementia" AND "music" AND "music therapy" AND "randomized controlled trial" AND "controlled clinical trial." Results: After reading and classifying the studies, this sample contained eight articles that addressed music therapy combined with different tools to determine its effectiveness. All of the listed articles used neuropsychological test batteries encompassing cognition, mood, functionality, social and support network assessment scales, and specific tests for Alzheimer's disease. It is noteworthy that non-pharmacological interventions, combined with pharmacological interventions, can be extremely beneficial for improving mood, sleep, quality of life, functionality, and even improving relationships between people with dementia and their families and caregivers. Final Considerations: The articles analyzed indicated the positive potential of music therapy as a tool for improving symptoms and quality of life in individuals with Alzheimer's disease. It is worth noting that no study was found that advocates or encourages the replacement of pharmacological treatment with non-pharmacological interventions.
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Organização Mundial da Saúde (OMS); Organização Pan-Americana de Saúde (OPAS). OMS revela as principais causas de morte e incapacidade em todo o mundo entre 2000 e 2019. Brasília (DF); 2020. Available from: https://www.paho.org/pt/noticias/9-12-2020-oms-revela-principais-causas-morte-e-incapacidade-em-todo-mundo-entre-2000-e
GBD 2019 Dementia Forecasting Collaborators. Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. Lancet Public Health. 2022;7:e105–25. Available from: https://doi.org/10.1016/S2468-2667(21)00249-8
American Psychiatric Association. Manual diagnóstico e estatístico de transtornos mentais: DSM-5. 5ª ed. Porto Alegre: Artmed; 2014.
Alzheimer’s Disease International. About Alzheimer's & Dementia. United Kingdom; 2022. Available from: https://www.alzint.org/about/
Sanders AE, Schoo C, Kalish VB. Vascular Dementia. StatPearls [Internet]. Treasure Island (FL); 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK430817/
Moraes EN, Marino MCA, Santos RP. Principais síndromes geriátricas. Rev Med Minas Gerais. 2010;20(1):54-66. Available from: https://rmmg.org/artigo/detalhes/383.
Freitas EV, Py L. Tratado de Geriatria e Gerontologia. 4ª ed. Rio de Janeiro: Guanabara Koogan; 2017.
Torres KROB, et al. Evolução das políticas públicas para a saúde do idoso no contexto do Sistema Único de Saúde. Rev Saúde Coletiva. 2020;30(1):1-22. Available from: https://www.scielo.br/j/physis/a/XqzFgPPbgmsKyJxFPBWgB3K/?lang=pt.
Zucchela C, et al. The multidisciplinary approach to Alzheimer's disease and dementia: a narrative review of non-pharmacological treatment. Front Neurol. 2018;9:1058. Available from: https://doi.org/10.3389/fneur.2018.01058
Organização Mundial da Saúde (OMS). Classificação Internacional de Funcionalidade, Incapacidade e Saúde. São Paulo: Editora da Universidade de São Paulo; 2008.
Gómez-Gallego M, Gómez-Gallego JC, Gallego-Mellado M, García-García J. Comparative efficacy of active group music intervention versus group music listening in Alzheimer’s disease. Int J Environ Res Public Health. 2021;18(15):8067. Available from: https://doi.org/10.3390/ijerph18158067
Gonzalez-Hoelling S, Bertran-Noguer C, Reig-Garci G, Suñer-Soler R. Effects of a music-based rhythmic auditory stimulation on gait and balance in subacute stroke. Int J Environ Res Public Health. 2021;18(4):2032. Available from: https://doi.org/10.3390/ijerph18042032
Steen JTV, et al. Music-based therapeutic interventions for people with dementia. Cochrane Database Syst Rev. 2018;7:CD003477. Available from: https://doi.org/10.1002/14651858.CD003477.pub4
Sampaio RF, Mancini MC. Estudos de revisão sistemática: um guia para síntese criteriosa da evidência científica. Braz J Phys Ther. 2007;11(1):83-9. Available from: https://doi.org/10.1590/S1413-35552007000100013
Innes KE, et al. Effects of meditation and music-listening on blood biomarkers of cellular aging and Alzheimer's disease in adults with subjective cognitive decline: an exploratory randomized clinical trial. J Alzheimers Dis. 2018;66(3):947-70. Available from: https://doi.org/10.3233/jad-180164
Giovagnoli AR, et al. Combining drug and music therapy in patients with moderate Alzheimer's disease: a randomized study. Neurol Sci. 2018;39(6):1021-8. Available from: https://doi.org/10.1007/s10072-018-3316-3
Sarkamo T, et al. Cognitive, emotional, and social benefits of regular musical activities in early dementia: randomized controlled study. Gerontologist. 2014;54(4):634-50. Available from: https://doi.org/10.1093/geront/gnt100
Sakamoto M, Ando H, Tsutou A. Comparing the effects of different individualized music interventions for elderly individuals with severe dementia. Int Psychogeriatr. 2013;25(5):775-84. Available from: https://doi.org/10.1017/s1041610212002256
Giovagnoli AR, et al. Cognitive training in Alzheimer's disease: a controlled randomized study. Neurol Sci. 2017;38(8):1485-93. Available from: https://doi.org/10.1007/s10072-017-3003-9
Samson S, et al. Efficacy of musical interventions in dementia: methodological requirements of nonpharmacological trials. Ann N Y Acad Sci. 2015;1337:249-55. Available from: https://doi.org/10.1111/nyas.12621
Satoh M, et al. Physical exercise with music maintains activities of daily living in patients with dementia: Mihama-Kiho Project Part 21. J Alzheimers Dis. 2017;57(1):85-96. Available from: https://doi.org/10.3233/jad-161217
Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-98. Available from: https://doi.org/10.1016/0022-3956(75)90026-6
Melo DM, Barbosa AJG. O uso do Mini-Exame do Estado Mental em pesquisas com idosos no Brasil: uma revisão sistemática. Ciênc Saúde Colet. 2015;20(12):3865-76. Available from: https://doi.org/10.1590/1413-812320152012.06032015
Brucki SMD, et al. Sugestões para o uso do mini-exame do estado mental no Brasil. Arq Neuropsiquiatr. 2003;61(3B):777-81. Available from: https://doi.org/10.1590/S0004-282X2003000500014
Jacobsen J, et al. Why musical memory can be preserved in advanced Alzheimer’s disease. Brain. 2015;138(8):2438-50. Available from: https://doi.org/10.1093/brain/awv135
Nascimento HG, Figueiredo AEB. Demência, familiares cuidadores e serviços de saúde: o cuidado de si e do outro. Ciênc Saúde Colet. 2019;24(4):1381-91. Available from: https://doi.org/10.1590/1413-81232018244.01212019
Zaro MA, et al. Emergência da neuroeducação: a hora e a vez da neurociência para agregar valor à pesquisa educacional. Ciênc Cognição. 2010;1(5):199-210. Available from: https://pepsic.bvsalud.org/scielo.php?script=sci_abstract&pid=S1806-58212010000100016
Bahar-Fuchs A, Clare L, Woods B. Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia. Cochrane Database Syst Rev. 2013;6:CD00326. Available from: https://doi.org/10.1002/14651858.cd003260.pub2
Yu F, et al. Cognitive effects of aerobic exercise in Alzheimer’s disease: a pilot randomized controlled trial. J Alzheimers Dis. 2021;80(1):233-44. Available from: https://doi.org/10.3233/JAD-201100
Costa TBL, Azevedo PF, Marquezi ML, Aparecido JML. Impacto do exercício físico no comportamento de idosas com Alzheimer. Enferm Foco. 2021;12(6):1151-8. Available from: https://dx.doi.org/10.21675/2357-707X.2021.v12.n6.4799
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