Nanoemulsões de compostos bioativos de base de plantas com aplicações antimicrobianas: uma revisão

Autores

DOI:

https://doi.org/10.5902/2179460X74325

Palavras-chave:

Atividade antimicrobiana, Nanopartículas, Produtos alternativos

Resumo

A busca por agentes antimicrobianos alternativos vem atraindo crescente interesse científico. Os produtos naturais de origem vegetal são fontes de diversas substâncias com atividades biológicas comprovadas, incluindo atividade antimicrobiana. O encapsulamento desses produtos na forma de nanoemulsão busca superar problemas inerentes a esses produtos, como instabilidade e degradação. Com base nessas considerações, realizamos um levantamento bibliográfico de nanoemulsões produzidas a partir de substâncias derivadas de plantas, como óleos essenciais e extratos, com potencial antimicrobiano, com foco nas atividades antibacteriana, antifúngica e antiviral. Foram utilizados artigos e documentos publicados em periódicos de relevância científica, bem como palavras-chave classificadas nos Descritores em Ciências da Saúde. Todos os documentos relevantes para esta pesquisa relataram que as nanoemulsões carregadas com óleos essenciais e extratos vegetais de diferentes espécies botânicas apresentaram atividade antimicrobiana in vitro contra diferentes microrganismos de importância médica, além de potencializar os efeitos antimicrobianos desses bioprodutos. Portanto, antimicrobianos nanoestruturados com óleos essenciais e extratos de plantas podem ser considerados opções de tratamento para doenças microbianas: devido às suas propriedades físico-químicas, atuam como melhores veículos de entrega de produtos naturais com boa biodisponibilidade, reduzindo a toxicidade e prolongando a vida útil desses antimicrobianos naturais, melhorando assim o tratamento de doenças humanas infecciosas.

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Biografia do Autor

Júlio César Sousa Prado, Universidade Federal do Ceará

Biólogo, Mestrando em Ciências da Saúde pela Universidade Federal do Ceará (UFC).

Guilherme Mendes Prado, Universidade Federal do Ceará

Farmacêutico, Mestre em Ciências da Saúde pela Universidade Federal do Ceará (UFC).

Francisca Lidiane Linhares Aguiar, Universidade Federal do Ceará

Bióloga, Doutora em Ciências Farmacêuticas pela Universidade Federal do Ceará (UFC).

Andrea Maria Neves, Universidade Estadual do Ceará

Bióloga, Doutora em Biotecnologia pela Universidade Estadual do Ceará (UECE).

Joice Farias do Nascimento, Universidade Estadual do Ceará

Química, Mestranda em Ciências Naturais pela Universidade Estadual do Ceará (UECE).

Flávia Oliveira Monteiro da Silva Abreu, Universidade Estadual do Ceará

Doutora em Engenharia de Minas, Metalúrgica e Materiais. Professora da Universidade Estadual do Ceará (UECE).

Raquel Oliveira dos Santos Fontenelle, Universidade Estadual Vale do Acaraú

Doutora em Ciências Veterinárias. Professora da Universidade Estadual Vale do Acaraú (UVA), Universidade Estadual do Ceará (UECE) e Universidade Federal do Ceará (UFC).

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2024-04-10

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Prado, J. C. S., Prado, G. M., Aguiar, F. L. L., Neves, A. M., Nascimento, J. F. do, Abreu, F. O. M. da S., & Fontenelle, R. O. dos S. (2024). Nanoemulsões de compostos bioativos de base de plantas com aplicações antimicrobianas: uma revisão. Ciência E Natura, 46, e74325. https://doi.org/10.5902/2179460X74325

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