Medicinal potential of tree vegetation for respiratory system treatment in southern Brazil
DOI:
https://doi.org/10.5902/2179460X86145Keywords:
Medicinal plants, Phytotherapy, Respiratory problemsAbstract
The Southern coal region of Santa Catarina concentrates 10.5% of Brazil's mineral coal reserves, and the ore extraction process has greatly contributed to the environmental degradation of the Urussanga River Basin in this region. At a global level, areas contaminated by coal mining cause public health concerns, owing to illnesses that may be associated with this practice, for example, respiratory diseases. In this context, the present study aimed to identify tree species with medicinal potential to treat respiratory diseases, sampled along the tributaries of the Urussanga River. For this purpose, a bibliographical review was conducted for 119 tree species recorded in the study area through a previous floristic survey. We searched the Scopus, SciELO, Science Direct, and PubMed databases for ethnobotanical and phytochemical studies that addressed the medicinal potential of these species for the respiratory system. Of the 119 species, 12 (10.08%) showed medicinal potential for the respiratory system. Of these, five were recommended for coughs and unspecified diseases affecting the respiratory tract, four for asthma, three for bronchitis, two for pneumonia, and one for laryngitis and acute lung problems. This finding highlights the medicinal potential of tree species native to Brazil present in the Urussanga River Hydrographic Basin region. However, further scientific studies are necessary to evaluate the phytochemical profile and pharmacological activity of these tree species from the Atlantic Forest biome, whose floristic composition has already been notably modified.
Downloads
References
Adami, R. M., & Cunha, Y. M. (2014). Caderno do educador ambiental das bacias dos rios Araranguá e Urussanga (2nd ed.). Blumenau: Fundação Agência de Água do Vale do Itajaí.
Alvares, C. A., Stape, J. L., Sentelhas, P. C., Golçalves, J. L. M., & Sparovek, G. (2013). Köppen’s climate classification map for Brazil. Meteorologische Zeitschrift, 22(6), 711-728. Retrieved from https://www.schweizerbart.de/papers/metz/detail/22/82078/Koppen_s_climate_classification_map_for_Brazil. doi: https://doi.org/10.1127/0941-2948/2013/0507 DOI: https://doi.org/10.1127/0941-2948/2013/0507
Alves, E. O., Mota, J. H., Soares, T. S., Vieira, M. C., & Silva, C. B. (2008). Levantamento etnobotânico e caracterização de plantas medicinais em fragmentos florestais de Dourados-MS. Ciências e agrotecnologia, 32(2), 651-658. Retrieved from https://www.scielo.br/j/cagro/a/FLQxcqYpkshCWggTpp8zbgf/?lang=pt. doi: https://doi.org/10.1590/S1413-70542008000200048. DOI: https://doi.org/10.1590/S1413-70542008000200048
Amorim, A. T., Sousa, J. A. P., & Lourenço, R. W. (2019). Indicador dos Estágios de Sucessão de Fragmentos Florestais do Bioma Mata Atlântica. Revista Brasileira de Cartografia, 71(3), 756-780. Retrieved from https://seer.ufu.br/index.php/revistabrasileiracartografia/article/view/48546. doi: https://doi.org/10.14393/rbcv71n3-48546. DOI: https://doi.org/10.14393/rbcv71n3-48546
Andrade-Silva, M., Cavalher-Machado, S. C., Formagio, A. S. N., Maris, R. S., Lima, O. M. Jr, Mello, S. V. B., Henriques, M. G. M. O., Arena, A. C., & Kassuya, C. A. L. (2020). Anti-inflammatory and anti-allergic activity of the methanolic extract from Annona sylvatica (Annonaceae). Genetics and Molecular Research, 19(3), 1-12. Retrieved from https://repositorio.unesp.br/items/5270b09a-aa79-4ad4-8523-3d3c66d9aa93. doi: http://dx.doi.org/10.4238/gmr18661 DOI: https://doi.org/10.4238/gmr18661
Araújo, J. J., Keller, H. A., & Hilgert, N. I. (2020). Syagrus romanzoffiana (Cham.) Glassman (Arecaceae) una palmera usada integralmente por los Guaraníes del Bosque Atlántico en el cono Sur de Sudamérica. In Hilgert, N. I., Pochettino, M. L., & Bermejo, E. H. (Org) Palmeras NUS al sur de la America Austral (pp. 39-56). Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo.
Batista, E. K. F., Trindade, H. I., Lira, S. R. S., Muller, J. B. B. S., Silva, L. L. B., & Batista, M. C. S. (2016). Atividades antinociceptiva e anti-inflamatória do extrato etanólico de Luehea divaricata. Revista Brasileira de Plantas Medicinais, 18(2), 433-441. Retrieved from https://www.scielo.br/j/rbpm/a/yQQwSx9XzSNB9sx4CdDsXKv/?lang=pt. doi: https://doi.org/10.1590/1983-084X/15_140. DOI: https://doi.org/10.1590/1983-084X/15_140
Bieski, I. G. C., Santos, F. R., Oliveira, R. M., Espinosa, M. M., Macedo, M., Albuquerque, U. P., & Martins, D. T. O. (2012). Ethnopharmacology of Medicinal Plants of the Pantanal Region (Mato Grosso, Brazil). Evidence-Based Complementary and Alternative Medicine, 2012(1), 1-36. Retrieved from https://onlinelibrary.wiley.com/doi/10.1155/2012/272749. doi: https://doi.org/10.1155/2012/272749. DOI: https://doi.org/10.1155/2012/272749
Bittencourt-Mernak, M. I., Pinheiro, N. M., Silva, R. C., Ponci, V., Banzato, R., Pinheiro, A. J. M. C. R., Olivo, C. R., Tibério, I. F. L. C., Neto, L. G. L., Santana, F. P. R., Lago, J. H., & Prado, C. M., (2021). Effects of Eugenol and Dehydrodieugenol B from Nectandra leucantha against Lipopolysaccharide (LPS)-Induced Experimental Acute Lung Inflammation. Journal of Natural Products, 84(8), 2282-2294. Retrieved from https://pubs.acs.org/doi/10.1021/acs.jnatprod.1c00386. doi: https://doi.org/10.1021/acs.jnatprod.1c00386. DOI: https://doi.org/10.1021/acs.jnatprod.1c00386
Blanco, G. D., Sühs, R. B., Brizola, E., Corrêa, P. F., Campos, M. L., & Hanazaki, N. (2020). Invisible contaminants and food security in former coal mining areas of Santa Catarina, Southern Brazil. Journal of Ethnobiology and Ethnomedicine, 16(44), 1-11. Retrieved from https://ethnobiomed.biomedcentral.com/articles/10.1186/s13002-020-00398-w. doi: https://doi.org/10.1186/s13002-020-00398-w. DOI: https://doi.org/10.1186/s13002-020-00398-w
Bolson, M., Hefler, S. M., Chaves, E. I. D., Gasparotto, A. Jr, & Cardozo, E. L. Jr. (2015). Ethno-medicinal study of plants used for treatment of human ailments, with residents of the surrounding region of forest fragments of Paraná, Brazil. Journal of Ethnopharmacology, 161, 1–10. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0378874114008630?via%3Dihub. doi: https://doi.org/10.1016/j.jep.2014.11.045. DOI: https://doi.org/10.1016/j.jep.2014.11.045
Borges, M. S., Amaral, P. A., & Citadini-Zanette, V. (2021a). Ethnobotanical study of selected medicinal plants used for the treatment of respiratory diseases in Southern Brazil. Journal of Medicinal Plants Research, 15(1), 22-34. Retrieved from https://academicjournals.org/journal/JMPR/article-abstract/4EB1D5F65786. doi: https://doi.org/10.5897/JMPR2020.6982. DOI: https://doi.org/10.5897/JMPR2020.6982
Borges, M. S., Amaral, P. A., & Citadini-Zanette, V. (2021b). O quintal medicinal de Dona Maria: Palntas medicinais utilizadas para o tratamento de doenças respiratórias. Criciúma: EdiUnesc.
Busnardo, T. C. P. M., Padoani, C., Mora, T. C., Biavatti, M. W., Fröde, T. S., Bürger, C., Claudino, V. D., Dalmarco, E. M., & Souza, M. M. (2010). Anti-inflammatory evaluation of Coronopus didymus in the pleurisy and paw oedema models in mice. Journal of Ethnopharmacology, 128(2), 519-525. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0378874109007727?via%3Dihub. doi: https://doi.org/10.1016/j.jep.2009.12.017 DOI: https://doi.org/10.1016/j.jep.2009.12.017
Carmona, F., Angelucci, M. A., Sales, D. S., Chiaratti, T. M., Honorato, F. B., Bianchi, R. V., & Pereira, A. M. S. (2013). Lippia alba (Mill.) N. E. Brown hydroethanolic extract of the leaves is effective in the treatment of migraine in women. Phytomedicine, 20(10), 947-950. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0944711313001268?via%3Dihub. doi: https://doi.org/10.1016/j.phymed.2013.03.017. DOI: https://doi.org/10.1016/j.phymed.2013.03.017
Carvalho, P. E. R. (2003). Cedro: Cedrela fissilis. Colombo: Embrapa Florestas. In Carvalho, P. E. R. Espécies arbóreas brasileiras (vol. 1, pp. 383-393). Brasília: Embrapa Informação Tecnológica; Colombo: Embrapa Florestas.
Coradin, L., Siminsk, A., & Reis, A. (2011). Espécies Nativas da Flora Brasileira de Valor Econômico Atual ou Potencial: Plantas para o Futuro: Região Sul. Brasília: MMA.
Correa, P. M. (1926). Dicionário das Plantas Úteis do Brasil e das Exóticas Cultivadas. Rio de Janeiro: Imprensa Nacional.
Cruz, M. G. (2008). Plantas Medicinais de Mato Grosso: A Farmacopeia Popular dos Raizeiros. Cuiabá: Carlini & Caniato.
Datasus. Tecnologia da Informação a Serviço do SUS. (2019). Morbidade Hospitalar do SUS por Local de Residência – Brasil. Internações por Unidade da Federação segundo Lista Morb CID-10. Retrieved from http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sih/cnv/nruf.def
Datasus. Tecnologia da informação a Serviço do SUS. (2024). Morbidade Hospitalar do SUS por Local de Residência – Brasil. Internações por Região segundo Capítulo CID-10, X-Doenças do aparelho respiratório. Retrieved from http://tabnet.datasus.gov.br/cgi/tabcgi.exe?sih/cnv/nruf.def.
Dias, A. P. L., Rinaldi, M. C. S., & Domingos, M. (2016). Foliar accumulation of polycyclic aromatic hydrocarbons in native tree species from the Atlantic Forest (SE-Brazil). Science of the Total Environment, 544(15), 175–184. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0048969715310731?via%3Dihub. doi: https://doi.org/10.1016/j.scitotenv.2015.11.092. DOI: https://doi.org/10.1016/j.scitotenv.2015.11.092
Dutra, A. F. (2018). Identificação, caracterização e controle in vitro e Phoma pedeiae (Aveskamp, Gruyter & Verkley) associado à Cedrela fissilis Vell (Ph.D’s thesis). Universidade Federal de Santa Maria, Santa Maria, RS, Brazil. Retrieved from https://repositorio.ufsm.br/handle/1/15107
Reflora. (2023). Flora e Funga Do Brasil. Jardim Botânico do Rio de Janeiro. Retrieved from http://floradobrasil.jbrj.gov.br/
Grecco, S. S., Lorenzi, H., Tempone, A. G., & Lago, J. H. G. (2016) Update: Biological and chemical aspects of Nectandra genus (Lauraceae). Tetrahedron Assymetr, 18, 793–810. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0957416616301665via%3Dihub. doi: https://doi.org/10.1016/j.tetasy.2016.07.009 DOI: https://doi.org/10.1016/j.tetasy.2016.07.009
Haldar, S., Kar, B., Dolai, M., Kumar, R. B. S., Behera, B., & Haldar, P. K. (2012). In vivo anti-nociceptive and anti-inflammatory activities of Lippia alba. Asian Pacific Journal of Tropical Disease, 2(2), 667-670. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S2222180812602412?via%3Dihub. doi: https://doi.org/10.1016/S2222-1808(12)60241-2. DOI: https://doi.org/10.1016/S2222-1808(12)60241-2
IBGE. (2012). Manual Técnico da Vegetação Brasileira. Rio de Janeiro: Instituto Brasileiro de Geografia e Estatística.
Kujawska, M., & Schmeda-Hirschmann, G. (2022). The use of medicinal plants by Paraguayan migrants in the Atlantic Forest of Misiones, Argentina, is based on Guaraní tradition, colonial and current plant knowledge. Journal of Ethnopharmacology, 283, 1-26. Retrieved
from https://www.sciencedirect.com/science/article/pii/S0378874121009314?via%3Dihub. doi:
https://doi.org/10.1016/j.jep.2021.114702. DOI: https://doi.org/10.1016/j.jep.2021.114702
Kujawska, M., Zamudio, F., & Hilger, N. I. (2012). Honey-Based Mixtures Used in Home Medicine by Nonindigenous Population of Misiones, Argentina. Evidence-Based Complementary and Alternative Medicine, 2012(1), 1-15. Retrieved from https://onlinelibrary.wiley.com/doi/10.1155/2012/579350. doi: https://doi.org/10.1155/2012/579350. DOI: https://doi.org/10.1155/2012/579350
Kusmardiyani, S., Suharli, Y. A., Insanu, M., & Fidrianny, I. (2020). Phytochemistry and pharmacological activities of Annona genus: A review. Current Research on Biosciences and Biotechnology, 2(1), 77-88. Retrieved from https://crbb-journal.com/ojs/index.php/crbb/article/view/36. doi: https://doi.org/10.5614/crbb.2020.2.1/KNIA7708. DOI: https://doi.org/10.5614/crbb.2020.2.1/KNIA7708
Lisbôa, G. N., Kinupp, V. F., & Barros, I. B. I. (2011). Eugenia involucrata Cerejeira-do-rio-grande. In Coradin, L., Siminski, A., & Reis, A. (Org.). Espécies Nativas da Flora Brasileira de Valor Econômico Atual ou Potencial: Plantas para o Futuro: Região Sul (pp. 163-168). Brasília: MMA.
Lopes, J. A., Rodrigues, V.P P., Tangerina, M. M. P., Rocha, L. R. M., Nishijima, C. M., Nunes, V. V. A., Almeida, L. F. R., Vilegas, W., Santos, A. R. S., Sannomiya, M., & Hiruma-Lima, C. A. (2020). Machaerium hirtum (Vell.) Stellfeld Alleviates Acute Pain and Inflammation: Potential Mechanisms of Action. Biomolecules, 10(4), 590. Retrieved from https://www.mdpi.com/2218-273X/10/4/590. doi: https://doi.org/10.3390/biom10040590. DOI: https://doi.org/10.3390/biom10040590
Mantena, S. K., Mutalik, S., Srinivasa, H., Subramanian, G. S., Prabhakar, K. R., Reddy, K. R., Srinivasan, K. K., & Unnikrishnan, M. K. (2005). Antiallergic, Antipyretic, Hypoglycemic and Hepatoprotective Effects of Aqueous Extract of Coronopus didymus LINN. Biological and Pharmaceutical Bulletin, 28(3), 468-472. Retrieved from https://www.jstage.jst.go.jp/article/bpb/28/3/28_3_468/_article. doi: https://doi.org/10.1248/bpb.28.468. DOI: https://doi.org/10.1248/bpb.28.468
Martins, H. B., Elias, G. A., Ceron, K., Antunes, A. R., Colares, R., Santos, R., & Citadini-Zanette, V. (2019). Estrutura do componente arbóreo das florestas ciliares na Bacia Hidrográfica do Rio Urussanga, sul de Santa Catarina, Brasil. Gaia Scientia, 13(3), 85-97. Retrieved from https://periodicos.ufpb.br/index.php/gaia/article/view/44174. doi: https://doi.org/10.22478/ufpb.1981-1268.2019v13n3.44174. DOI: https://doi.org/10.22478/ufpb.1981-1268.2019v13n3.44174
Menezes, C. T. B., & Waterkemper, K. (2013). Evolução dos processos de degradação ambiental resultante da mineração de carvão em Santa Catarina de 1930-1973. In Milioli, G., Santos, R., & Citadini-Zanette, V. (Org.). Mineração de carvão, meio ambiente e desenvolvimento sustentável no Sul de Santa Catarina: uma abordagem interdisciplinary (pp. 205-213). Curitiba: Juruá.
Mentz, L., Lutzenberger, L. C., & Schenkel, E. P. (1997). Da flora medicinal do Rio Grande do Sul: notas sobre a obra de D’ávila (1910). Caderno de Farmácia, 13(1), 25-48. Retrieved from https://lume.ufrgs.br/handle/10183/19288.
Ministério da Saúde. (2010). Cadernos de Atenção Básica: Doenças respiratórias crônicas. Brasília: MS. Retrieved from https://bvsms.saude.gov.br/bvs/publicacoes/doencas_respiratorias_cronicas.pdf.
Perez, L., Rapp, R., & Künzli, N. (2010). The year of the lung: Outdoor air pollution and lung health. Swiss Medical Weekly, 140(4546), 6–10. Retrieved from https://smw.ch/index.php/smw/article/view/1214. doi: https://doi.org/10.4414/smw.2010.13129. DOI: https://doi.org/10.4414/smw.2010.13129
Petroni, L. M, Huffman, M. A., & Rodrigues, E. (2017). Medicinal plants in the diet of woolly spider monkeys (Brachyteles arachnoides, E. Geoffroy, 1806) – a bio-rational for the search of new medicines for human use? Revista Brasileira de Farmacognosia, 27(2), 135–142. Retrieved from https://www.sciencedirect.com/science/article/pii/S0102695X16303593?via%3Dihub. doi: https://doi.org/10.1016/j.bjp.2016.09.002. DOI: https://doi.org/10.1016/j.bjp.2016.09.002
Ponci, V., Silva, R. C., Santana, F. P. R., Grecco, S. S., Fortunato, C. R. M., Oliveira, M. A., Tavares-de-Lima, W., Olivo, C. R., Tibério, I. F. L. C., Gomes, K. S., Prado, C. M., & Lago, J. H. G. (2020). Biseugenol Exhibited Anti-Inflammatory and Anti-Asthmatic Effects in an Asthma Mouse Model of Mixed-Granulocytic Asthma. Molecules, 25(22), 5384. Retrieved from https://www.mdpi.com/1420-3049/25/22/5384. doi: https://doi.org/10.3390/molecules25225384. DOI: https://doi.org/10.3390/molecules25225384
Pott, A, & Pott, V. J. (1994). Plantas do Pantanal. Brasília: Embrapa.
Pramchoo, W., Geater, A. F., Jamulitrat, S., Geater, Tangtrakulwanich, B. (2017). Occupational tasks influencing lung function and respiratory symptoms among charcoal-production workers: A time-series study. Safety Health Work, 3(8), 250–257. Retrieved from https://www.sciencedirect.com/science/article/pii/S2093791116303225?via%3Dihub. doi: https://doi.org/10.1016/j.shaw.2016.11.006. DOI: https://doi.org/10.1016/j.shaw.2016.11.006
Pubmed. National Library of Medicine. (2023). Retrieved from https://pubmed.ncbi.nlm.nih.gov/.
Ranasinghe, P., Pigera, S., Premakumara, G. A. S., Galappaththy, P., Constantine, G. R., & Katulanda, P. (2013). Medicinal properties of ‘true’ cinnamon (Cinnamomum zeylanicum): a systematic review. Bmc Complementary And Alternative Medicine, 13(275), 1-10. Retrieved from https://bmccomplementmedtherapies.biomedcentral.com/articles/10.1186/1472-6882-13-275. doi: https://doi.org/10.1186/1472-6882-13-275 DOI: https://doi.org/10.1186/1472-6882-13-275
Ranjan, R. (2019). Avaliando o impacto da mineração no desmatamento na Índia. Política de Recursos, 60, 23-35.
Ribeiro, D. L., Cilião, H. L., Specian, A. F. L., Serpeloni, J. M., Souza, M .F., 1, Tangerina, M. M. P., Vilegas, W., Boldrin, P. K., Resende, F. A., Varanda, E. A., Martínez-López, W., Sannomiya, M., & Cólus, I. M. S. (2016). Chemical and biological characterisation of Machaerium hirtum (Vell.) Stellfeld: absence of cytotoxicity and mutagenicity and possible chemopreventive potential. Mutagenesis, 31(2), 147–160. Retrieved from https://academic.oup.com/mutage/article-abstract/31/2/147/2622766?redirectedFrom=fulltext&login=false. doi: https://doi.org/10.1093/mutage/gev066 DOI: https://doi.org/10.1093/mutage/gev066
Ricardo, L. M., Paula-Souza, J., Andrade, A., & Brandão, M. G. L. (2017). Plants from the Brazilian Traditional Medicine: species from the books of the Polish physician Piotr Czerniewicz (Pedro Luiz Napoleão Chernoviz, 1812–1881). Revista Brasileira de Farmacognosia, 27(3), 388–400. Retrieved from https://www.sciencedirect.com/science/article/pii/S0102695X16303684?via%3Dihub. doi:
https://doi.org/10.1016/j.bjp.2017.01.002. DOI: https://doi.org/10.1016/j.bjp.2017.01.002
Rodrigues, C. G., Vormittag, E. M. P. A., Cavalcante, J. A., & Saldiva, P. H. N. (2015). Projeção da mortalidade e internações hospitalares na rede pública de saúde atribuíveis à poluição atmosférica no Estado de São Paulo entre 2012 e 2030. Revista Brasileira de Estudos de População, 3(32), 489–509. Retrieved from https://www.scielo.br/j/rbepop/a/rTK8kvKYpXcBy7SS5KWNVHR/?lang=pt. doi: https://doi.org/10.1590/S0102-3098201500000029 DOI: https://doi.org/10.1590/S0102-3098201500000029
Santana, F. P. R., Silva, R. C., Ponci, V., Pinheiro, A. J. M. C. R., Olivo, C. R., Caperuto, L. C., Arantes-Costa, F. M., Claudio, S. R., Ribeiro, D.A., Tibério, I. F. L. C., Lima-Neto, L. G., Lago, J. H. G., & Prado, C. M. (2020). Dehydrodieugenol improved lung inflammation in an asthma model by inhibiting the STAT3/SOCS3 and MAPK pathways. Biochemical Pharmacology, 180, 1-14. Retrieved from https://www.sciencedirect.com/science/article/pii/S0006295220304111?via%3Dihub. doi: https://doi.org/10.1016/j.bcp.2020.114175. DOI: https://doi.org/10.1016/j.bcp.2020.114175
Scopus. Elsevier B.V. (2023). Retrieved from https://www.scopus.com/home.uri.
SciELO.org. Scientific Electronic Library Online. (2023). Retrieved from https://scielo.org/.
ScienceDirect. Elsevier B.V. (2023). Retrieved from https://www.sciencedirect.com/.
Sharifi-Rad, J., Dey, A., Koirala, N., Shaheen, S., El Omari, N., Salehi, B., Goloshvili, T., Silva, N. C. C., Bouyahya, A., Vitalini, S., Varoni, E. M., Martorell, M., Abdolshahi, A., Docea, A. O., Iriti, M., Calina, D., Les, F., López, V., & Caruntu, C. (2021). Cinnamomum Species: bridging phytochemistry knowledge, pharmacological properties and toxicological safety for health benefits. Frontiers in Pharmacology, 12, 1-27. Retrieved from https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.600139/full. doi: https://doi.org/10.3389/fphar.2021.600139 DOI: https://doi.org/10.3389/fphar.2021.600139
Silva, B. P., & Parente, J. P. (2010). Chemical properties and antiinflammatory activity of a galactomannoglucan from Arecastrum romanzoffianum. Phytochemistry Letters, 3, 109-112. Retrieved from
https://www.sciencedirect.com/science/article/abs/pii/S1874390010000236?via%3Dihub. doi: https://doi.org/10.1016/j.phytol.2010.02.007. DOI: https://doi.org/10.1016/j.phytol.2010.02.007
Tanaka, J. C. A., Silva, C. C., Dias Filho, B. P., Nakamura, C. V., Carvalho, J. E., & Foglio, M. A. (2005). Chemical constituents of Luehea divaricata Mart. (Tiliaceae). Química Nova, 28(5), 834–837. Retrieved from https://www.scielo.br/j/qn/a/ZtnrpKWfRg98pk7RsH9mDLs/?lang=pt. doi: https://doi.org/10.1590/S0100-40422005000500020. DOI: https://doi.org/10.1590/S0100-40422005000500020
Touché, G. E. (2004). Ecological sustainability, environmental justice, and energy use: an annotated bibliography. Journal of Planning Literature, 19(2), 206-223. Retrieved from https://journals.sagepub.com/doi/10.1177/0885412204268091. doi: https://doi.org/10.1177/0885412204268091 DOI: https://doi.org/10.1177/0885412204268091
Vendruscolo, G. S., Simões, C. M. O., & Mentz, L. A. (2005). Etnobotânica no Rio Grande do Sul: Análise Comparativa Entre o Conhecimento Original e Atual Sobre as Plantas Medicinais Nativas. Pesquisa botânica, 56, 285-322. Retrieved from https://www.scienceopen.com/document?vid=8fd55edb-a2e0-4878-89db-7cb636259848
Vieira, M.R., Amaral, I., Watanuri, M. M., Souza, C. G. N. M., & Augustini, J. A. (2016). Manual Ilustrado de Pragas em Cedro (Cedrela fissilis Vellozo). Ilha Solteira: Unesp.
Zacchino, S., Santecchia, C., López, S., Gattuso, S., Muñoz, J. D., Cruañes, A., Vivot, E., Cruañes, M. C., Salinas, A., Ruiz, R. E., & Ruiz, S. (1998). In vitro antifungal evaluation and studies on mode of action of eight selected species from the argentine flora. Phytomedicine, 5(5), 389–395. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0944711398800226?via%3Dihub. doi: https://doi.org/10.1016/S0944-7113(98)80022-6. DOI: https://doi.org/10.1016/S0944-7113(98)80022-6
Yazbek, P. B., Matta, P., Passero, L. F., Santos, G., Braga, S., Assunção, L., Sauini, T., Cassas, F., Garcia, R. J. F., Honda, S., Barreto, E. H. P., Rodrigues, E. (2019). Plants utilized as medicines by residents of Quilombo da Fazenda, Núcleo Picinguaba, Ubatuba, São Paulo, Brazil: A participatory survey. Journal of Ethnopharmacology, 244, 1-12. Retrieved from https://www.sciencedirect.com/science/article/abs/pii/S0378874118342144?via%3Dihub. doi: https://doi.org/10.1016/j.jep.2019.112123 DOI: https://doi.org/10.1016/j.jep.2019.112123
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Ciência e Natura
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
To access the DECLARATION AND TRANSFER OF COPYRIGHT AUTHOR’S DECLARATION AND COPYRIGHT LICENSE click here.
Ethical Guidelines for Journal Publication
The Ciência e Natura journal is committed to ensuring ethics in publication and quality of articles.
Conformance to standards of ethical behavior is therefore expected of all parties involved: Authors, Editors, Reviewers, and the Publisher.
In particular,
Authors: Authors should present an objective discussion of the significance of research work as well as sufficient detail and references to permit others to replicate the experiments. Fraudulent or knowingly inaccurate statements constitute unethical behavior and are unacceptable. Review Articles should also be objective, comprehensive, and accurate accounts of the state of the art. The Authors should ensure that their work is entirely original works, and if the work and/or words of others have been used, this has been appropriately acknowledged. Plagiarism in all its forms constitutes unethical publishing behavior and is unacceptable. Submitting the same manuscript to more than one journal concurrently constitutes unethical publishing behavior and is unacceptable. Authors should not submit articles describing essentially the same research to more than one journal. The corresponding Author should ensure that there is a full consensus of all Co-authors in approving the final version of the paper and its submission for publication.
Editors: Editors should evaluate manuscripts exclusively on the basis of their academic merit. An Editor must not use unpublished information in the editor's own research without the express written consent of the Author. Editors should take reasonable responsive measures when ethical complaints have been presented concerning a submitted manuscript or published paper.
Reviewers: Any manuscripts received for review must be treated as confidential documents. Privileged information or ideas obtained through peer review must be kept confidential and not used for personal advantage. Reviewers should be conducted objectively, and observations should be formulated clearly with supporting arguments, so that Authors can use them for improving the paper. Any selected Reviewer who feels unqualified to review the research reported in a manuscript or knows that its prompt review will be impossible should notify the Editor and excuse himself from the review process. Reviewers should not consider manuscripts in which they have conflicts of interest resulting from competitive, collaborative, or other relationships or connections with any of the authors, companies, or institutions connected to the papers.
