Antibacterial screening of hexane extracts from Psidium myrtoides, a Brazilian native plant

Authors

DOI:

https://doi.org/10.5902/2179460X84178

Keywords:

Natural antimicrobials, Hexane extracts, Brazilian cerrado

Abstract

Even though Brazil has a large biodiversity of medicinal plants, many of them have not had their chemical and biological potential acknowledged. Several medicinal plants are rich in secondary metabolites with broad antibacterial activity, a relevant fact since many pathogenic bacteria are resistant to conventional antibiotics. Psidium myrtoides, a species of plant in the Myrtaceae family that is known for its sweet purple fruit, should be highlighted in this field. It is a medicinal plant with strong antibacterial, antifungal, anti-inflammatory, antioxidant, antitumoral, and herbicidal potential. This study aimed at investigating, for the first time, the antibacterial activity of hexane extracts from P. myrtoides dry leaves – which were collected in both dry and rainy seasons – and the dry pericarp of unripe fruit. Their antibacterial activity was evaluated in vitro by the broth microdilution method on 96-well plates, and their Minimum Inhibitory Concentration (MIC) values were expressed as µg/mL. The following bacteria were assayed: Streptococcus mutans, S. sobrinus, S. mitis, S. salivarius, S. sanguinis, Enterococcus faecalis, Lactobacillus casei, Xanthomonas citri (resistant, tolerant, and sensitive to copper), Mycobacterium tuberculosis, M. avium, and M. kansasii. The resulting MIC values of all extracts under study were promising since they ranged from 31.25 to 500 µg/mL. This study revealed the in vitro potential of P. myrtoides against different bacterial strains and reinforced the need for further phytochemical investigations that aim at isolating its bioactive chemical constituents.

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Author Biographies

Anderson Martins Rodrigues Ribeiro, Instituto Federal Goiano

Master's degree in Agrochemistry from IFGoiano – Rio Verde Campus.

Cassia Cristina Fernandes, Instituto Federal Goiano

PhD in Chemistry from the Federal Rural University of Rio de Janeiro.

Ralciane de Paula Menezes, Universidade Federal de Uberlândia

Doutorado em Ciências da Saúde pela Universidade Federal de Uberlândia.

Andreia Marques de Oliveira, Universidade Federal de Uberlândia

Graduanda em Biomedicina pela Universidade Federal de Uberlândia.

Daniela Silva Gonçalves, Universidade Federal de Uberlândia

Graduanda em Biomedicina pela Universidade Federal de Uberlândia (UFU). 

Carlos Henrique Gomes Martins, Universidade Federal de Uberlândia

Doutorado em Biociências pela Universidade Estadual Paulista Júlio de Mesquita Filho, UNESP.

Mayker Lazaro Dantas Miranda, Universidade Federal do Triângulo Mineiro

PhD in Chemistry from the Federal University of Mato Grosso do Sul - UFMS.

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Published

2024-11-22

How to Cite

Ribeiro, A. M. R., Fernandes, C. C., Menezes, R. de P., Oliveira, A. M. de, Gonçalves, D. S., Martins, C. H. G., & Miranda, M. L. D. (2024). Antibacterial screening of hexane extracts from Psidium myrtoides, a Brazilian native plant. Ciência E Natura, 46, e84178. https://doi.org/10.5902/2179460X84178