Clinical and economic impact of Antimicrobial Stewardship Program in a school hospital in Brazil

Authors

DOI:

https://doi.org/10.5902/2236583467943

Keywords:

Agentes Anti-infecciosos, Serviço de Farmácia Clínica, Redução de Custos, Serviços de Controle de Infecção Hospitalar,

Abstract

Antimicrobials are one of the most prescribed drug classes in hospital environments, generating high health costs, in addition to being co-responsible for bacterial resistance. This study aimed to evaluate the clinical and economic impacts of the Antimicrobial Stewardship Program in a school hospital in the hinterland of Rio Grande do Sul, Brazil. Methods: Antimicrobials were analyzed according to their indication, dose, duration of treatment, and route of administration. Whenever needed, interventions with the prescribing physician or nursing staff were performed to optimize the therapy. Results: A total of 1288 medical prescriptions underwent pharmaceutical analysis. It was carried out 71 interventions, including interventions with medical staff and nursing staff, with an acceptance rate of 75% and 100%, respectively. The cost savings achieved during the study period (5 months) was R$ 5,921.84. The vast majority of patients in the intervention group had a positive outcome, progressing to discharge (86.96%). There was an 18.3% reduction in the Daily Defined Dose of intravenous ciprofloxacin between May and July. Conclusion: This study highlights the positive aspects of using the Antimicrobial Stewardship Program as an effective strategy in reducing costs and consuming antimicrobials without negative impacts on patients’ clinical outcomes.

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Author Biographies

Luiz Eduardo Bulegon Brondani, University of Santa Cruz do Sul

Farmacêutico formado pela Universidade Federal de Santa Maria (UFSM), tendo ênfase em Farmácia Industrial no desenvolvimento de formulações farmacêuticas. Especialista em Saúde na Área Temática de Intensivismo, Urgência e Emergência e Área de Concentração em Atenção em Urgência e Emergência pelo Hospital Santa Cruz, em Santa Cruz do Sul - RS. Especialista em Farmácia Hospitalar e Clínica pelo Hospital Moinhos de Vento, Porto Alegre - RS. Especialista em Farmácia Clínica e Hospitalar em Oncologia pela Faculdade Unyleya. Atualmente Farmacêutico na Prefeitura Municipal de Santa Maria - RS.

Ana Paula Helfer, University of Santa Cruz do Sul

Professora do Departamento de Biologia e Farmácia, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, RS, Brasil.

Eliane Carlosso Krummenauer, University of Santa Cruz do Sul

Vice-coordenadora da Comissão de Controle de Infecção e Epidemiologia Hospitalar, Hospital Santa Cruz, Santa Cruz do Sul, RS, Brasil.

Jane Dagmar Pollo Renner, University of Santa Cruz do Sul

Professora do Departamento de Biologia e Farmácia e do Programa de Pós-Graduação em Promoção da Saúde, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, RS, Brasil.

Marcelo Carneiro, University of Santa Cruz do Sul

Professor do Departamento de Biologia e Farmácia e do Programa de Pós-Graduação em Promoção da Saúde, Universidade de Santa Cruz do Sul, Santa Cruz do Sul, RS, Brasil

Rochele Mosmann Menezes, University of Santa Cruz do Sul

Membro executivo da Comissão de Controle de Infecção e Epidemiologia Hospitalar, Hospital Santa Cruz, Santa Cruz do Sul, RS, Brasil.

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Published

2024-04-26

How to Cite

Brondani, L. E. B., Helfer, A. P., Krummenauer, E. C., Renner, J. D. P., Carneiro, M., & Menezes, R. M. (2024). Clinical and economic impact of Antimicrobial Stewardship Program in a school hospital in Brazil. Saúde (Santa Maria), 50(1). https://doi.org/10.5902/2236583467943

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Vol. 50 No. 1 (2024): Revista Saúde (Santa Maria) | Fluxo contínuo

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