An approach towards the reconstruction of regulatory networks

Autores

DOI:

https://doi.org/10.5902/2448190422639

Palavras-chave:

Bioinformatics, Computer Science, Transcriptional Regulatory Networks, Data Integration

Resumo

Currently, one of the main issues addressed in the bioinformatics field is understanding the structure and behaviour of complex molecular interaction networks. Since most of the information available belongs to biomedical literature, a large part of this task entails selecting the relevant articles from a large body of papers. However, due to the rapidly increasing number of scientific papers, it is quite difficult to read all  the  papers that have been published about this subject. In order to accomplish this, this work is focused on developing methods for retrieving information from biological databases, gathering as much information as possible; to create an integrated repository, that is able to store and load this data and also to design a pipeline to allow the reconstruction of regulatory networks through using Biomedical Text Mining techniques.

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Biografia do Autor

Rafael Teodósio Pereira, University of Minho

Rafael Teodósio Pereira is Ph.D student in Informatics at University of Minho. He has degree in Computer Science  at Centro Universitário Franciscano, Santa Maria/ Brasil, and Master in Bioinformatics at University of Minho, Braga/Portugal. He is a member of the reserach groups: Bioinformatics and Systems Biology Interdisciplinary Initiative (University of Minho); Computational Physics, Complex Systems, Genetic Theory (Federal University of Santa Maria); Programming Languages and Data Bases (Federal University of Santa Maria). His research interests include: ontologies; biological databases; pervasive computing; reconstruction of regulatory models; strain optimization and metabolic engineering. His current work includes development an integrated repository containing the data relevant for the regulatory reconstruction, as well as computational tools for the loading of the data and its integration, together will application for querying curating the available data to provide a computational platform for the reconstruction of genome-scale regulatory models.

Referências

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Publicado

2016-10-11

Como Citar

Pereira, R. T., Costa, H., & Mendes, R. (2016). An approach towards the reconstruction of regulatory networks. Revista ComInG - Communications and Innovations Gazette, 1(2), 15–25. https://doi.org/10.5902/2448190422639

Edição

v. 1 n. 2 (2016): Segunda Edição

Seção

Artigos científicos

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