Sepsis protocol in brazilian hospitals: epidemiological analysis and clinical insights

análisis epidemiológico y insights clínicos

Authors

DOI:

https://doi.org/10.5902/2236583493734

Keywords:

Septic shock, Hospital infection control program, Epidemiological profile

Abstract

This letter discusses sepsis, a leading cause of death in Latin America, particularly in Brazil, where it significantly impacts pediatric and adult patients. It highlights the importance of the data from the study by Benetti et al. (2020), which reveals the high incidence of sepsis in pediatric hospitals, adding practical Brazilian results on the implementation of the protocol against the disease in the country. Sepsis is a preventable cause of death in low- and middle-income countries (LMICs), with Brazil playing a central role in addressing the issue. Between 2022 and 2023, a survey conducted by the Antimicrobial Stewardship Group Brazil (ASP-BR) found that 61.4% of the 863 surveyed hospitals had a sepsis protocol. Notably, 15.8% of these hospitals lacked an intensive care unit (ICU), and a significant portion of hospitals in rural areas had smaller capacities. The study underscores the need for multi-disciplinary teams, particularly nurses, to play a key role in initiating sepsis protocols. In line with Benetti et al., the letter stresses the importance of timely sepsis recognition during the "golden hour" and adherence to Surviving Sepsis Campaign guidelines. It also calls for increased human and financial resources to combat sepsis effectively, in alignment with the UN’s Sustainable Development Goals. The letter advocates for a robust system to track health indicators and improve emergency and critical care services, positioning sepsis as a silent emergency requiring urgent action from healthcare professionals.

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Author Biographies

Lucas Augusto Hochscheidt, Universidade de Santa Cruz do Sul

Acadêmico do Curso de Graduação em Medicina, Universidade de Santa Cruz do Sul (UNISC), Santa Cruz do Sul, Rio Grande do Sul.

Géssica Milani Carneiro, Universidade de Santa Cruz do Sul

Mestranda do Programa de Pós-Graduação em Promoção da Saúde - Epidemiologia, Universidade de Santa Cruz do Sul (UNISC), Santa Cruz do Sul, Rio Grande do Sul.

Marcelo Carneiro, Universidade de Santa Cruz do Sul

Doutor em Ciências Médicas, Universidade de Santa Cruz do Sul (UNISC), Santa Cruz do Sul, Rio Grande do Sul.

Magda Machado de Miranda Costa, Agência Nacional de Vigilância Sanitária

Mestra em Gestão da Qualidade em Serviços de Saúde, Agência Nacional de Vigilância Sanitária (ANVISA).

Mara Rubia Santos Gonçalves, Agência Nacional de Vigilância Sanitária

Graduada em Farmácia, Agência Nacional de Vigilância Sanitária (ANVISA).

References

Benetti MB, Weinmann ARM, Jacobi LF, Moraes AB. Unidade de Terapia Intensiva Pediátrica: perfil das internações e mortalidade. Revista Saúde (Sta. Maria). 2020;46(1):1-12.

Azevedo LC, Cavalcanti AB, Lisboa T, Dal-Pizzol FD, Machado FR. A sepse é um grave problema de saúde na América Latina: uma chamada à ação. Rev Bras Ter Intensiva. 2018;30(4):402-404.

Assis MP, Ziembowicz H, Menezes RM, Gonçalves MRS, Costa MMM, Carneiro M. Stewardship in Brazil: a call for action. Clin Infect Dis. 2024;78(4):1073-1075.

Carneiro M, Fernandes R, Telles JP, Makdisse M, Vidal CFL; Brazilian Collaborative on Antimicrobial Stewardship. The role of value-based healthcare in enhancing antimicrobial stewardship for end-of-life patients. Clin Infect Dis. 2025;80(2):475.

Instituto Latino Americano de Sepse. Implementação de protocolo gerenciado de sepse [Internet]. 2018 [cited 2025 Jan 03]. Available from: https://ilas.org.br/wp-content/uploads/2022/02/protocolo-de-tratamento.pdf

Published

2026-10-29

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